Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
نویسندگان
چکیده
منابع مشابه
Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
The cesium carbonate-mediated reaction of 2-bromoallyl sulfones and ortho-hydroxychalcones furnished 3-arylsulfonyl-4H-chromene derivatives in 58-67% yield (18 examples). 2-Bromoallyl sulfones functioned as synthetic surrogates for allenyl sulfones in the reaction.
متن کاملFacile and convenient synthesis of 2-amino-5,10-dioxo-4-aryl-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile derivatives by electrocatalytically chemical transformation
2-Amino-5,10-dioxo-4-aryl-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile derivatives are obtained in excellent yields with a simple and efficient procedure.This reaction can occur using electrocatalytic multicomponent chain transformation of aryl aldehydes, 2-hydroxynaphthalene-1,4-dione and malononitrile under neutral and mild conditions. Moreover, electrolysis is done in CH3CN as solvent, Te...
متن کاملLi(OHCH2CH2NH2)(CF3OAC): A novel and homogeneous acidic ionic liquid catalyst for efficient synthesis of 2-amino-4H-chromene derivatives
The ionic liquid Li(OHCH2CH2NH2)(CF3OAC) was found to efficiently catalyze the three-component reaction between different enols, aldehydes, and malononitrile , leading to rapid synthesis of 2-amino-4H-chromene derivatives in fairly high yields. The catalyst is easily prepared, highly stable, simple to handle and recycled for several times without significant loss of activity. The method is simp...
متن کاملTiO2/nanoclinoptilolite, a recyclable and high efficient heterogeneous nanocatalyst, for the synthesis of 2-amino-4H-chromene derivatives
The synthesis of pharmaceutically and biologically active 2-amino-4H-chromenes was described using TiO2/nanoclinoptilolite (TiO2/NCP) as an efficient nanocatalyst under solvent-free condition. The TiO2/NCP was fabricated through modification of NCP with HDTMA, then the surface modified NCP was impregnated with titanium tetrachloride solution. Finally, the materi...
متن کاملLi(OHCH2CH2NH2)(CF3OAC): A novel and homogeneous acidic ionic liquid catalyst for efficient synthesis of 2-amino-4H-chromene derivatives
The ionic liquid Li(OHCH2CH2NH2)(CF3OAC) was found to efficiently catalyze the three-component reaction between different enols, aldehydes, and malononitrile , leading to rapid synthesis of 2-amino-4H-chromene derivatives in fairly high yields. The catalyst is easily prepared, highly stable, simple to handle and recycled for several times without significant loss of activity. The method is simp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Beilstein Journal of Organic Chemistry
سال: 2016
ISSN: 1860-5397
DOI: 10.3762/bjoc.12.3